SnoaW/SnoaL2: A Different Two-Component Monooxygenase

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• 作者：Andreas Bechthold¹ ; ^{andreas.bechthold@pharmazie.uni-freiburg.de} ; Xiaohui Yan¹
• 刊名：Chemistry & Biology
• 出版年：2012
• 期刊代码：20_10745521
• 类别：ch
• 出版时间：25 May, 2012
• 卷：19
• 期：5
• 页码：549-551
• 文件大小：203 K

摘要

The hydroxylation of C-1 in nogalamycin is an essential step in its biosynthesis. Siitonen and colleagues, in聽this issue of Chemistry & Biology, reveal an unconventional mechanism for the hydroxylation of the 3鈥?4鈥?demethoxy-nogalose-nogalamycinone by a two-component monoxygenase SnoaW/SnoaL2.