Hidden depression in otolaryngology patients with medically unexplained symptoms

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• 作者：Fumiyuki Goto ; M.D. ; Ph.D.^a ; ^{amifumi@bc5.so-net.ne.jp} ; Tomoko Tsutsumi ; M.D.^a ; Naoki Oishi ; M.D.^b ; Masaru Mimura ; M.D. ; Ph.D.^c
• 关键词：Medically unexplained symptoms ; Depression ; Antidepressant ; Selective serotonin reuptake inhibitors
• 刊名：General Hospital Psychiatry
• 出版年：2012
• 期刊代码：107_01638343
• 类别：med
• 出版时间：March-April, 2012
• 卷：34
• 期：2
• 页码：206-208
• 文件大小：198 K

摘要

Objective

To investigate the prevalence of depression among otolaryngology patients with medically unexplained symptoms (MUS) and the outcome of treatment with selective serotonin reuptake inhibitors (SSRIs).

Method

Ninety patients with MUS from a population of 983 consecutive otolaryngology outpatients were enrolled. The Self-Rating Depression Scale (SDS) was used to screen for depression. In addition to standard treatment, all depressed and nondepressed patients received SSRIs for 8 weeks. The Clinical Global Impression-Improvement (CGI-I) scale was used to evaluate clinical changes in patients with MUS.

Results

There were 49 patients with depression among those with MUS, according to the SDS criteria. The patients with depression showed a better outcome than those without depression, demonstrating more significantly improved CGI-I scores.

Conclusion

More than half of the individuals with otolaryngological MUS had depression, and their MUS were successfully treated with聽SSRIs.