Rhabdomyolysis due to primary hyperaldosteronism
- 作者：José ; Joaquí ; n Alfaro Martí ; nez ; jalfaro@ono.com ; Cristina Lamas Oliveira ; Amparo Lomas Meneses ; Silvia Aznar Rodrí ; guez ; Pedro Piné ; s Corrales ; Antonio Herná ; ndez Ló ; pez ; Francisco Botella Romero
- 关键词：Rhabdomyolysis ; Hyperaldosteronism ; Adrenal adenoma
- 刊名：Endocrinolog铆a y Nutrici贸n
- 出版年：2009
- 期刊代码：pca151_15750922
- 类别：med
- 出版时间：October 2009
- 卷：56
- 期：8
- 页码：431-434
- 文件大小：175 K
摘要
Rhabdomyolysis may be secondary to trauma, excessive muscle activity, hereditary muscle enzyme defects and other medical causes. Primary hyperaldosteronism is characterised by hypertension, hypokalemia, suppressed plasma renin activity, and increased aldosterone excretion. Rhabdomyolysis is not common in primary hyperaldosteronism. We report here a 42-year-old woman presenting with rhabdomyolysis as heralding symptom of primary hyperaldosteronism. We also carried out a search of the literature to identify all cases of rhabdomyolysis as the firstrecognized expression of a primary hyperaldosteronism. Sixteen cases met the criteria for inclusion. When rhabdomyolysis occurs in a patient with hypokalemia and metabolic alkalosis, primary hyperaldosteronism has to be suspected: if confirmed, an aldosterone-producing adenoma is the most probable cause.