Asymmetric electrochemical oxidation of 1,2-diols, aminoalcohols, and aminoaldehydes in the presence of chiral copper catalyst
- 作者：Daishirou Minato ; Hitomi Arimoto ; Yoko Nagasue ; Yosuke Demizu ; Osamu Onomura
- 关键词：Asymmetric electrochemical oxidation ; Copper complex ; 1 ; 2-Diol ;
//www.sciencedirect.com/scidirimg/entities/204e.gif" alt="greek small letter alpha" title="greek small letter alpha" border="0">-Ketoalcohol ; Aminoalcohol ; Aminoaldehyde
- 刊名：Tetrahedron
- 出版年：2008
- 期刊代码：107_00404020
- 类别：ch
- 出版时间：7 July 2008
- 卷：64
- 期：28
- 页码：6675-6683
- 文件大小：789 K
摘要
Asymmetric oxidation of 1,2-diols, aminoalcohols, and aminoaldehydes in the presence of copper(II) triflate and (R,R)-Ph-BOX was accomplished by electrochemical method using Br− as a mediator. This oxidation was applicable to kinetic resolution of racemic cis-cycloalkane-1,2-diols, aminoalcohols, and aminoaldehydes to afford optically active compounds with good to high enantioselectivity.