Prognostic value of circulating pregnancy-associated plasma protein-A (PAPP-A) and proform of eosinophil major basic protein (pro-MBP) levels in patients with chronic stable angina pectoris
- 作者：Luciano Consuegra-Sanchez ; Ivana Petrovic ; Juan Cosin-Sales ; David W. Holt ; Michael Christiansen ; Juan Carlos Kaski
- 关键词：PAPP-A ; pro-MBP ; Long-term mortality ; Chronic stable angina
- 刊名：Clinica Chimica Acta
- 出版年：2008
- 期刊代码：54_00098981
- 类别：med
- 出版时间：May 2008
- 卷：391
- 期：1-2
- 页码：18-23
- 文件大小：324 K
摘要
Pregnancy-associated plasma protein-A (PAPP-A) concentrations predict outcome in patients with acute coronary syndromes. PAPP-A levels and PAPP-A/pro-MBP ratio are increased in chronic stable angina (CSA) patients with complex coronary artery stenoses. Little is known however, about the long-term prognostic value of PAPP-A and pro-MBP in “real-life” CSA patients. We sought to assess whether PAPP-A, the proform of eosinophil major basic protein (pro-MBP) and PAPP-A/pro-MBP levels predict long-term all-cause mortality in patients with CSA.