• 作者：E. Reyna-Villasmil ; ^{sippenbauch@gmail.com} ; J. Mejia-Montilla ; N. Reyna-Villasmil ; J. Santos-Bolí ; var ; D. Torres-Cepeda ; E. Peñ ; a-Paredes
• 关键词：Preeclampsia ; Eclampsia ; Adiponectina ; Hipertensió ; n
• 刊名：Cl铆nica e Investigaci贸n en Ginecolog铆a y Obstetricia
• 出版年：2009
• 期刊代码：pca89_0210573X
• 类别：med
• 出版时间：January-February 2009
• 卷：36
• 期：1
• 页码：13-18
• 文件大小：374 K

Objective

To establish adiponectin concentrations in eclamptic, preeclamptic and normotensive pregnant women and to compare blood pressure values according to serum concentrations.

Material and methods

This study included 30 patients with mild preeclampsia (group A), 30 patients with severe preeclampsia (group B) and 30 patients with eclampsia (group C). Controls were selected because they were of a similar age and body mass index to patients in the study groups and consisted of 35 healthy pregnant women (group D). Blood samples for serum adiponectin determination were collected from all patients before delivery and immediately after diagnosis in the study groups.

Results

Statistically significant differences were found in gestational age between groups B and C compared with controls (P<.05). Adiponectin values were lowest in groups B and C and highest in group A and were significantly lower in all the study groups than in controls (group D, P<.05). When adiponectin concentrations were correlated with systolic and diastolic blood pressure values, a strong negative and significant correlation was found (P<.05).

Conclusions

Serum adiponectin concentrations were lower in eclamptic and preeclamptic patients than in normotensive pregnant women and a strong negative correlation was found between serum concentrations and systolic blood pressure.