Short and valid assessment of apraxia in Parkinson鈥檚 disease

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• 作者：T. Vanbellingen^a ; ^b ; C. Lungu^c ; G. Lopez^c ; F. Baronti^d ; R. Mü ; ri^a ; ^b ; M. Hallett^c ; S. Bohlhalter^b ; ^e ; ^{stephan.bohlhalter@luks.ch}
• 关键词：Apraxia ; Validity ; AST ; Parkinson&rsquo ; s disease
• 刊名：Parkinsonism and Related Disorders
• 出版年：2012
• 期刊代码：215_13538020
• 类别：med
• 出版时间：May, 2012
• 卷：18
• 期：4
• 页码：348-350
• 文件大小：155 K

摘要

Background

Valid assessment of apraxia in usually non-apraxic Parkinson鈥檚 disease helps to delineate atypical parkinsonism frequently associated with apraxia. Furthermore, in a subgroup of late Parkinson鈥檚 disease apraxia, typically the ideomotor subtype, may gradually superimpose onto parkinsonian motor symptoms contributing to defective manual skill. Here we evaluate the utility of a brief, standardized test, the apraxia screen of TULIA (AST).

Methods

Seventy five Parkinson鈥檚 disease patients were tested with the AST. Parkinsonian motor deficits were measured using Movement Disorders Society-Unified Parkinson鈥檚 Disease Rating Scale (MDS-UPDRS) part III and difficulties in activities of daily living (ADL) by modified MDS-UPDRS part II (eating, dressing, personal hygiene, and writing).

Results

No association was found between the AST and MDS-UPDRS part III, indicating that AST discriminates well (discriminative validity) between apraxia and parkinsonism. Furthermore, AST was associated with ADL and Hoehn & Yahr stage (convergent validity).

Conclusions

AST is a short and valid test to rule out or detect apraxia in Parkinson鈥檚 disease.