A novel method for the synthesis of 5-substituted 1H-tetrazole from oxime and sodium azide

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• 作者：Umakant B. Patil ; Kedar R. Kumthekar ; Jayashree M. Nagarkar ; ^{jm.nagarkar@ictmumbai.edu.in} ; ^{jayashreenagarkar@yahoo.co.in}
• 关键词：5-Substituted 1H-tetrazole ; [3+2] Cycloaddition ; Oxime ; Cu(OAc)2
• 刊名：Tetrahedron Letters
• 出版年：2012
• 期刊代码：109_00404039
• 类别：ch
• 出版时间：18 July, 2012
• 卷：53
• 期：29
• 页码：3706-3709
• 文件大小：2381 K

摘要

A simple and efficient protocol is developed for the synthesis of 5-substituted 1H-tetrazoles from various oximes and sodium azide (NaNb>3b>) by using copper acetate as a catalyst.