• 作者：Silvia Franco Hidalgo^a ; ^{silvi26pras@hotmail.com} ; Esther Herná ; ndez Garc&#237 ; a^b ; Alberto Palmeiro Uriach^c ; José ; Mar&#237 ; a Monfá ; Bosh^b ; Victoria Oviedo Gó ; mez^b ; Fernando Sousa Pé ; rez^b ; Josefa Mart&#237 ; n Gago^b ; Luisa Sá ; nchez Garc&#237 ; a^b ; Paula Mart&#237 ; n Escuer^b ; Fernando Arranz Arija^d
• 关键词：Carcinoma de cé ; lulas de Merkel ; Tumores cutá ; neos ; Trasplantados renales ; Terapia inmunosupresora
• 刊名：Di谩lisis y Trasplante
• 出版年：2010
• 期刊代码：pca116_18862845
• 类别：med
• 出版时间：October-December 2010
• 卷：31
• 期：4
• 页码：127-129
• 文件大小：848 K

Merkel cell carcinoma (MCC) is an infrequent tumor of cells of the basal layer of the epidermis or dermis and is related to sun exposure and the immune system. The risk of developing MCC is greater in renal transplant recipients than in the general population. In these patients, this tumor develops at younger ages and in multiple locations; in addition, this entity is more aggressive, more frequently recurs after treatment, and is associated with other tumors of the skin and with hematologic neoplasms. We describe the case of a 68-year-old male renal transplant recipient who developed multiple epidermoid carcinomas and MCC with regional metastasis after 4 years of receiving immunosuppressive therapy.