Dietary exposure to polychlorinated dibenzo-p-dioxins, polychlorinated dibenzofurans and polychlorinated biphenyls of the French population: Results of the second French Total Diet Study

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• 作者：Vé ; ronique Sirot^a ; ^{sirotv@gmail.com} ; Alexandra Tard^a ; ¹ ; Anaï ; s Venisseau^b ; ^c ; Aline Brosseaud^b ; ^c ; Philippe Marchand^b ; ^c ; Bruno Le Bizec^b ; ^c ; Jean-Charles Leblanc^a
• 关键词：Dietary exposure ; PCDD ; PCDF ; PCB ; Total Diet Study
• 刊名：Chemosphere
• 出版年：2012
• 期刊代码：15_00456535
• 类别：env
• 出版时间：July, 2012
• 卷：88
• 期：4
• 页码：492-500
• 文件大小：325 K

摘要

Polychlorinated dibenzo-p-dioxins (PCDDs), polychlorinated dibenzofurans (PCDFs) and polychlorinated biphenyls (PCBs) bioaccumulate through the food chain and are therefore of public health concern. Exposure to these compounds was assessed in the second French Total Diet Study (TDS). Food samples (n = 583) were collected to be representative of the whole diet of the population, prepared as consumed, and analyzed. Contamination data were combined with national individual food consumption data.

Mean exposure (95th percentile) to PCDD/F + DL-PCBs was assessed to be 0.57 (1.29) pg TEQ_WHO-98 (kg bw)^鈭? d^鈭? in the adult population and 0.89 (2.02) pg TEQ_WHO-98 (kg bw)^鈭? d^鈭? in the child and teenager population. Less than 4%of the population exceeded the health-based guidance value for PCDD/F + DL-PCBs. Mean exposure (95th percentile) to the six indicator PCBs (PCB 28, 52, 101, 138, 153, 180) was estimated at 2.71 (7.90) ng (kg bw)^鈭? d^鈭? in the adult population and 3.77 (11.7) ng (kg bw)^鈭? d^鈭? in the child and teenager population. Only 2.6%of the adults [CI_95%: 1.9; 3.3] and 6.5%of the children and teenagers [5.2; 7.8] exceeded the health-based guidance value for total PCBs.

These results show that the contamination levels in food and therefore the exposure of the general French population to PCDD/Fs and PCBs have declined (by a factor of 3.2 for PCDD/F + DL-PCBs and about three for total PCBs) since the last evaluation, which was conducted using another methodology in 2005 and 2007, and show the efficiency of the European risk management measures which came into force after these evaluations.