Preparation of microgel-supported chiral catalysts and their application in the asymmetric hydrogenation of aromatic ketones

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• 作者：Jia Deng ; Cuifen Lu ; ^{lucf@hubu.edu.cn} ; Guichun Yang ; Zuxing Chen
• 关键词：Microgel-supported ; TsDPEN ; Catalyst ; Asymmetric hydrogenation ; Aromatic ketones
• 刊名：Reactive and Functional Polymers
• 出版年：2012
• 期刊代码：92_13815148
• 类别：ch
• 出版时间：June, 2012
• 卷：72
• 期：6
• 页码：378-382
• 文件大小：249 K

摘要

An enantiomerically pure chiral monomer (S,S)-2 was prepared and copolymerized with styrene and four different cross-linkers to produce four distinct microgel-supported chiral TsDPEN derivatives. These chiral copolymers were allowed to form complexes with [RuCl₂(cymene)]₂ and the resulting homogeneous catalysts were applied in asymmetric hydrogenation reactions of aromatic ketones to give enantioenriched secondary alcohols in quantitative yield. These polymeric catalysts can be easily separated from the reaction mixture and recycled several times without a significant loss in catalytic activity.