The use of monodentate phosphites and phosphoramidites as effective ligands for Rh-catalyzed asymmetric hydrogenation in supercritical carbon dioxide

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• 作者：S.E. Lyubimov ; E.E. Said-Galiev ; A.R. Khokhlov ; N.M. Loim ; L.N. Popova ; P.V. Petrovskii ; V.A. Davankov
• 关键词：Monodentate phosphites ; Asymmetric hydrogenation ; Rhodium ; Supercritical carbon dioxide
• 刊名：The Journal of Supercritical Fluids
• 出版年：2008
• 期刊代码：60_08968446
• 类别：ce
• 出版时间：May 2008
• 卷：45
• 期：1
• 页码：70-73
• 文件大小：225 K

摘要

Series of chiral monodentate phosphite-type ligands has been evaluated in the rhodium-catalyzed asymmetric hydrogenation of dimethyl itaconate in both dichloromethane and supercritical CO₂. High reactivities (100%conversion in 1.5–3 h) and enantioselectivities (up to 90%) were obtained in the hydrogenation in scCO₂.