Correlation of current perception threshold and somatosensory evoked potential in diabetes

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• 作者：W. Zheng^a ; ^{mm25.52mm@163.com} ; Y. He^b ; L. Chen^c
• 关键词：Current perception threshold ; Somatosensory evoked potential ; Diabetic neuropathy
• 刊名：Neurophysiologie Clinique / Clinical Neurophysiology
• 出版年：2012
• 期刊代码：204_09877053
• 类别：med
• 出版时间：June, 2012
• 卷：42
• 期：4
• 页码：241-247
• 文件大小：231 K

摘要

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Summary

Objective

To study the relationship between current perception threshold (CPT) and somatosensory evoked potential (SEP) in diabetes.

Methods

Both CPT and SEP were recorded in 66 diabetic patients. Both the CPT scores (measured at 2000 Hz, 250 Hz, and 5 Hz stimulations) and SEP (peak latency at ERB's point [Lat _ERB] and popliteal fossa [Lat _PF]; interpeak latency of 鈥淓RB to 7th cervical vertebra鈥?[螖lat _ERB-C7] and 鈥減opliteal fossa to lumbar vertebra鈥?[螖lat _PF-FO]) were recorded in both upper and both lower limbs, separately. t-tests and correlation analyses were performed to assess relationships between CPT and SEP tests.

Results

After adjustment for height and/or age, CPT scores at 2000 Hz were significantly correlated with Lat _ERB (left: 蟻 = 0.408, P < 0.05; right: 蟻 = 0.297, P < 0.05), 螖lat _ERB-C7 (left: 蟻 = 0.238, P < 0.05; right: 蟻 = 0.385, P < 0.05), and Lat _PF (蟻 = 0.216, P < 0.05), and those at 250 Hz were moderately correlated with Lat _ERB (left: 蟻 = 0.234, P < 0.05; right: 蟻 = 0.306, P < 0.05). CPT scores at 5 Hz were not significantly correlated with any SEP measurements (P > 0.05).

Conclusions

Both CPT scores at 2000 Hz and SEP may reliably determine large-fiber function in diabetic neuropathy.