Prevalence of epilepsy in the 15 years and older in Benin: A door-to-door nationwide survey

详细信息	查看全文 | 推荐本文 |

• 作者：Luce-Perrine Yemadje^a ; ^b ; ^{luce.yemadje@etu.unilim.fr} ; Dismand Houinato^a ; ^b ; ^{dshouinato@yahoo.fr} ; Farid Boumé ; diè ; ne^a ; ^c ; ^{farid.boumediene@unilim.fr} ; Edgar Brice Ngoungou^a ; ^d ; ^{ngoungou2001@yahoo.fr} ; Pierre-Marie Preux^a ; ^{preux@unilim.fr} ; Michel Druet-Cabanac^a ; ^{michel.druet-cabanac@unilim.fr}
• 关键词：Door-to-door screening ; Epilepsy ; Nationwide survey ; Benin ; Prevalence
• 刊名：Epilepsy Research
• 出版年：2012
• 期刊代码：87_09201211
• 类别：med
• 出版时间：May, 2012
• 卷：99
• 期：3
• 页码：318-326
• 文件大小：460 K

摘要

| Figures/TablesFigures/Tables | ReferencesReferences

Summary

Purpose

Estimate the prevalence of epilepsy in the 15 years and older in Benin.

Methods

We used a random multistage sampling design to select a representative sample of the 15 years and older in Benin. From March to May 2010, people were screened door-to-door in the twelve regions of Benin. Screening and data collection were performed using a validated standardised questionnaire of epilepsy in tropical regions. A neurologist examined all people suspected of epilepsy.

Results

We identified 174 suspected epilepsy cases from 13,046 screened people; 105 were confirmed by the neurologist (54 men and 51 women). The mean age of PWE was 28.9 卤 14.3 years. The estimate of crude prevalence of epilepsy in the 15 years and older in Benin was 8.05/1000 (95%CI: 6.52-9.58/1000). The crude prevalence of epilepsy among men was 9.77/1000 (95%CI 7.35-12.73/1000) and 6.79/1000 (95%CI 5.06-8.91/1000) for women. The age-adjusted prevalence of epilepsy on sub-Saharan Africa population was 8.25/1000 and 7.33/1000 on world population. Substantial heterogeneity was noted, with differences from one region to another. The most common seizure types were generalised tonic-clonic (80.0%), partial secondary generalised seizures (14.3%) and partial seizures (5.7%).

Significance

This nationwide study is the first in West Africa. It provides a low prevalence of epilepsy in Benin compared to previous studies performed in this country and in neighbouring countries. Restricted-area studies are often motivated by the presence of specific risk factors and could overestimate the prevalence, while large-scale studies could underestimate other subtle forms of epilepsy.