摘要
The model refers to a treatment design or to a block-treatment design in the presence of non-stochastic covariates, attached to each experimental unit. The problem is that of most efficient estimation of covariates parameters on one side and the treatment contrasts and/or block contrasts on the other side. If the components in the two sides are “orthogonal”, then we can invoke optimality [in some sense] separately in each side and thereby characterize optimal designs in such a set-up.