- 作者：Donahue ; PhD ; Richard P. ; Prineas ; MD ; Ronald J. ; Bean ; PhD ; Judy A. ; Donahue ; PhD ; Rosemary A. Decarlo ; et. al.
- 关键词：Insulin ; Blood Pressure ; African-American ; Hispanic-American ; Cross-Sectional Study. ; CHD = coronary heart disease ; IGT = impaired glucose tolerance ; BMI = body mass index ; WHR = waist-to-hip ratio ; CT = computed tomography
- 刊名：Annals of Epidemiology
- 出版年：1998
- 期刊代码：15_10472797
- 类别：med
- 出版时间：May, 1998
- 卷：8
- 期：4
- 页码：236-244
- 文件大小：341 K
METHODS: A cross-sectional study was performed among 25–44-year-old African-Americans , Cuban-Americans , and non-Hispanic whites selected from Date County, Florida. Fasting insulin levels were correlated with resting blood pressure level within each ethnic group. The separate effects of percentage body fat and waist girth on the association between blood pressure and insulin were analyzed in multiple linear regression and analysis of covariance.
RESULTS: Fasting insulin was positively associated with systolic (; P < 0.01) and diastolic blood pressure (; to P < 0.001) among women of all ethnic groups and among non-Hispanic white men (; P < 0.05). Stepwise linear regression analyses revealed statistically significant associations between systolic and diastolic blood pressure and fasting insulin level in non-Hispanic whites independent of other covariates, including sex and percentage body fat (P < 0.001). Fasting insulin was also independently and significantly related to systolic blood pressure among African-Americans . Among Cuban-Americans, sex and percentage body fat were the main correlates of blood pressure level. Analysis of covariance revealed a relationship between insulin and blood pressure that was independent of waist girth among men and women.
CONCLUSIONS: Fasting insulin level and blood pressure were positively associated among African-Americans and non-Hispanic whites. This association was not entirely due to the common association with percentage body fat or waist girth.