Focusing on the issue of ESL development tools, this paper describes an MPSoC environment design which targets the Multidimensional Intensive Signal Processing (MISP) application domain. Within this environment, we have defined first a generic execution model that supports any type of MPSoC. It can adapt to any parallel application and handle efficiently the scheduling and synchronizations at all the levels of granularity. Second, a new Virtual Processor (VP) based simulation technique is proposed for implementing the execution model. This proposal leverages the high-level specification of the system to provide a heterogeneous MPSoCs simulation without using an Instruction Set Simulator (ISS). VP-based simulation is implemented in SystemC at a timed transactional level allowing a good trade-off between high simulation speed and performance estimation accuracy. The usefulness and the effectiveness of our MPSoC environment is illustrated through two MISP applications executed on a typical MPSoC. Results show that our approach enables fast MPSoC virtual prototyping, data transfers and timing analysis, and reliable DSE for architectural optimizations.