The gas monitoring system for the Resistive Plate Chamber detector of the CMS experiment at LHC
- 作者：M. Abbrescia ; A. Colaleo ; R. Guida ; G. Iaselli ; F. Loddo ; M. Maggi ; B. Marangelli ; S. Natali ; S. Nuzzo ; G. Pugliese ; A. Ranieri ; F. Romano ; G. Roselli ; R. Trentadue ; S. Tupputi ; L. Benussi ; M. Bertran
- 关键词：Contrast nephropathy ; NGAL ; Cystatin C ; Coronary artery disease ; PCI
- 刊名：Nuclear Physics B - Proceedings Supplements
- 出版年：2008
- 期刊代码：46_09205632
- 类别：ph
- 出版时间：March 2008
- 卷：177-178
- 期：Complete
- 页码：293-296
- 文件大小：251 K
摘要
The aim of the study was to assess whether NGAL and cystatin C could predict contrast-induced nephropathy in non-diabetic patients (n = 60, mean age 60 ± 11 years) with normal serum creatinine undergoing elective PCI. We found a significant rise in serum NGAL after 2, 4 and 8 h, and in urinary NGAL after 4, 8 and 24 h after PCI. Cystatin C rose significantly 8 and 24 h after the procedure. Prevalence of CIN was 10%. We found 90%sensitivity and 74%specificity of serum and 76%sensitivity and 80%specificity of urinary NGAL increase. NGAL may represent a sensitive early biomarkers of renal impairment after PCI.