• 作者：Leandro Damiá ; n Sousa^a ; ^{leandro-d-sousa@hotmail.com} ; Florencia Rafael^b ; Rodrigo Santamarina^a ; Sergio Gonorazky^a ; Diana Scharovsky^c
• 关键词：Anosognosia ; Demencia ; Deterioro cognitivo ; Queja mné ; sica ; Reserva cognitiva
• 刊名：Neurolog铆a Argentina
• 出版年：2010
• 期刊代码：pca377_18530028
• 类别：neu
• 出版时间：April-June 2010
• 卷：2
• 期：2
• 页码：119-124
• 文件大小：397 K

Memory complaints are described more frequently in subject with mild cognitive impairment than in normal subjects and in those with diagnostic of dementia, decreasing as the demential syndrome progresses. There are differences between different studies, what has led to search for other factors involved. The aim of the present work is to determine to what extent the patient and the caregiver are aware of the deficit, and to analyze the influence of variables like sex, degree of cognitive impairment and educational level.

Consecutive patients from the cognitive department of our institution were selected between January 2004 and December 2007, inclusive. The following variables were collected: age, sex, degree of cognitive deterioration, years of education and the answer to the question about the mnesic complaints made to the patient and the caregiver. A univariable analysis and logistic regression were performed.

Seven hundred and twenty two patients were identified, with a median age of 76 years; 84%of them recognized to have memory problems. Increasing cognitive impairment was associated with less aware of the amnesic deficit (p = 0,003). Eighty-six percent (86%) of the caregivers perceived memory impairment in patients, which increased with the progression of amnesic deterioration (p < 0,001) and educational degree (p < 0,001).

In our series, the patient's memory complaints decrease as the cognitive impairment progresses. The caregivers recognize more defects when the impairment increases, and when patient's schooling degree is higher.