The radioprotector Bowman–Birk proteinase inhibitor stimulates DNA repair via epidermal growth factor receptor phosphorylation and nuclear transport

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• 作者：Klaus Dittmann ; Claus Mayer ; Rainer Kehlbach ; H. Peter Rodemann
• 关键词：BBI ; EGFR ; TP53 ; DNA repair ; MDC1
• 刊名：Radiotherapy and Oncology
• 出版年：2008
• 期刊代码：231_01678140
• 类别：med
• 出版时间：March 2008
• 卷：86
• 期：3
• 页码：375-382
• 文件大小：714 K

摘要

The purpose of the study was to elucidate the underlying molecular mechanism of the radioprotector, Bowman–Birk proteinase inhibitor (BBI), and its interaction with EGFR nuclear transport.