• 作者：M.J. Frade Mera ; ^{mariajesusfrade@yahoo.es} ; A. Guirao Moya ; M.E. Esteban Sá ; nchez ; J. Rivera Á ; lvarez ; A.M. Cruz Ramos ; B. Bretones Chorro ; S. Viñ ; as Sá ; nchez ; S. Jacue Izquierdo ; M. Montane Ló ; pez
• 关键词：Escala ; Sedació ; n ; Ventilació ; n mecá ; nica ; Cuidados Intensivos ; Monitoreo fisioló ; gico
• 刊名：Enfermer铆a Intensiva
• 出版年：2009
• 期刊代码：pca155_11302399
• 类别：med
• 出版时间：July-September 2009
• 卷：20
• 期：3
• 页码：88-94
• 文件大小：295 K

Background

This study aimed to verify the relationship between different Sedation Rating Scales (SRSs) for critical patients on mechanical ventilation and to know the relationship between the SRSs, clinical information and the dose of sedative and analgesia drugs (SAD).

Material and methods

A longitudinal, prospective analytic pilot study conducted in a Medical-Surgical Intensive Care Unit of a tertiary hospital from October-December 2006. The sample included patients who required administration of SAP and mechanical ventilation. The following biological parameters and scales were evaluated: patient's demographics, RAMSAY, Sedation Agitation Scale (SAS), Richmond Agitation Sedation Scale (RASS), Motor Activity Assessment Scale (MASS), SAD dose, mean blood pressure, cardiac rate, pupil diameter and respiratory frequency. Spearman coefficient of interrelation was used to compare the relationship between the different scales.

Results

A total of 2.412 measurements were made for each variable: SRS, clinical information and SAD dose in 30 patients with different diseases, 63%males, age 52 卤 19 years, APACHEII 24 卤 8, SAPSII 44 卤 16, with an ICU mortality UCI 34%. Median and IQ range of stay in ICU 15.5 and 20 days, of mechanical ventilation 9 and 14 days, of SAD 6 and 5.5 days and of paralyzing drugs (PD) 2 and 5 days, respectively. Interrelation was detected between all the SRSs, with p < 0.0001. The relationship between SAS, RASS and MASS was direct, whereas these were related inversely to RAMSAY. No evidence of interrelation was found between the SRSs, the clinical information and the SAD doses.

Conclusion

The RAMSAY scale that has not been validated in ICU patients has a strong interrelation with the other already validated SRSs. SRSs are subjective and do not correlate with the clinical information and the SAD doses, probably due to the sample's small size and heterogeneity.