One-pot sequential Baylis脙脙脙脙脙脙Hillman and Michael reactions

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• 作者：Wang ; Wengui ; Yu ; Marvin
• 关键词：Baylis脙脙脙脙脙脙Hillman ; Michael ; Sequential ; One-pot ; DBU ; Multi-component
• 刊名：Tetrahedron Letters
• 出版年：2004
• 期刊代码：109_00404039
• 类别：ch
• 出版时间：September 13, 2004
• 卷：45
• 期：38
• 页码：7141-7143
• 文件大小：250 K

摘要

A new one-pot procedure for the sequential Baylis芒芒芒Hillman and Michael reactions has been developed to construct two carbon芒芒芒carbon bonds with three components. This procedure has been applied to combine a variety of aromatic aldehydes, 芒芒-unsubstituted acrylates and activated methide nucleophiles to generate highly diversified and functionalized organic compounds.