Comparison of noninvasive continuous arterial waveform analysis (Nexfin) with transthoracic Doppler echocardiography for monitoring of cardiac output

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• 作者：Anna G.E. van der Spoel ; MD ; MSC^a ; ¹ (Resident) ; Albertus J. Voogel ; MD ; PhD^b ; ¹ (Staff Cardiologist) ; Anja Folkers ; BSc^b (Echocardiography Technician) ; Christa Boer ; PhD^a (Associate Professor) ; R. Arthur Bouwman ; MD ; PhD^a ; ^{a.bouwman@vumc.nl} (Staff Anesthesiologist)
• 关键词：Arterial pulse contour analysis ; Cardiac output ; Doppler echocardiography ; Method comparison ; Validation studies
• 刊名：Journal of Clinical Anesthesia
• 出版年：2012
• 期刊代码：147_09528180
• 类别：med
• 出版时间：June, 2012
• 卷：24
• 期：4
• 页码：304-309
• 文件大小：251 K

摘要

Study Objectives

To compare the Nexfin cardiac output (CO) with the CO obtained from transthoracic Doppler echocardiography (TTE) during routine cardiac function screening.

Design

Observational clinical study.

Setting

Echocardiography laboratory.

Patients

40 ASA physical status 1 and 2 patients scheduled for routine TTE examination.

Interventions

None.

Measurements and Main Results

In 40 patients scheduled for routine TTE examination, we obtained simultaneous CO measurements with Doppler ultrasound and derived from Nexfin blood pressure measurements. Correlation and level of agreement between Nexfin and TTE were analyzed using Pearson correlation coefficient and Bland-Altman plots. The Pearson correlation coefficient for Nexfin versus TTE was 0.68 (CI: 0.46 - 0.82, P < 0.0001). Bland-Altman analysis showed a bias of 0.51 卤 1.1 L/min and limits of agreement of -1.6 to 2.6 L/min, with a percentage error of 39%.

Conclusions

Considering limits of precision of CO measurements with Doppler echocardiography (卤 30%), the agreement between noninvasive CO measurement with the Nexfin and TTE is reasonable.