Management of elderly patients with breast cancer: updated recommendations of the International Society of Geriatric Oncology (SIOG) and European Society of Breast Cancer Specialists (EUSOMA)

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• 作者：Dr Laura Biganzoli ; MD^a ; ^{lbiganzoli@usl4.toscana.it} ; Hans Wildiers ; MD^b ; Catherine Oakman ; MD^a ; Lorenza Marotti ; BSc^c ; Sibylle Loibl ; MD^d ; Ian Kunkler ; FRCR^e ; Prof Malcolm Reed ; MD^f ; Stefano Ciatto ; MD^g ; Adri C Voogd ; PhD^h ; Etienne Brain ; MDⁱ ; Bruno Cutuli ; MD^j ; Catherine Terret ; MD^k ; Prof Margot Gosney ; MD^l ; Matti Aapro ; MD^m ; Prof Riccardo Audisio ; MDⁿ
• 刊名：Lancet Oncology
• 出版年：2012
• 期刊代码：184_14702045
• 类别：med
• 出版时间：April, 2012
• 卷：13
• 期：4
• 页码：e148-e160
• 文件大小：123 K

摘要

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Summary

As the mean age of the global population increases, breast cancer in older individuals will be increasingly encountered in clinical practice. Management decisions should not be based on age alone. Establishing recommendations for management of older individuals with breast cancer is challenging because of very limited level 1 evidence in this heterogeneous population. In 2007, the International Society of Geriatric Oncology (SIOG) created a task force to provide evidence-based recommendations for the management of breast cancer in elderly individuals. In 2010, a multidisciplinary SIOG and European Society of Breast Cancer Specialists (EUSOMA) task force gathered to expand and update the 2007 recommendations. The recommendations were expanded to include geriatric assessment, competing causes of mortality, ductal carcinoma in situ, drug safety and compliance, patient preferences, barriers to treatment, and male breast cancer. Recommendations were updated for screening, primary endocrine therapy, surgery, radiotherapy, neoadjuvant and adjuvant systemic therapy, and metastatic breast cancer.