Poor repertoire General Movements predict some aspects of development outcome at 2 years in very preterm infants

详细信息	查看全文 | 推荐本文 |

• 作者：Elisa Beccaria^a ; ^{beccaria.e@ospedale.cuneo.it} ; Manuela Martino^a ; Eleonora Briatore^a ; Barbara Podestà ; ^a ; Giulia Pomero^b ; Rocco Micciolo^c ; Giuseppe Espa^d ; Stefano Calzolari^a
• 关键词：Preterm infants ; Griffiths Scales of Mental Development ; General Movements ; Infant neurodevelopment ; Eye and hand coordination
• 刊名：Early Human Development
• 出版年：2012
• 期刊代码：82_03783782
• 类别：med
• 出版时间：June, 2012
• 卷：88
• 期：6
• 页码：393-396
• 文件大小：150 K

摘要

Background

Observation of the quality of endogenously generated 鈥淕eneral Movements鈥?has been proved to be a reliable and sensitive tool in the assessment of fragile neonates. The absence of fidgety movements at 2-4 months post-term is highly predictive of Cerebral Palsy. On the contrary, the presence of a poor repertoire pattern during the writhing period is not reliable in predicting motor or neurobehavioral disorders at any stage of development.

Aim

To examine if the presence of a PR pattern at 1 month post-term was associated with lower neurodevelopmental quotients at 2 years.

Study design

General Movements evaluation at 1 and 3 months and the Griffiths Scales of Mental Development at 2 years were administered to a sample of very preterm infants. Infants were divided into two groups: poor repertoire pattern group and normal pattern group. Student's t Test and Chi squared test and ANOVA were used to compare neonatal variables and results between the two groups.

Subjects

79 very preterm infants (birthweight 鈮?#xA0;1500 g or gestational age 鈮?#xA0;32 weeks), born January 2003 to December 2006 who had a follow-up at 2 years.

Outcome measure

Griffiths developmental quotient at 2 years.

Results

The Poor Repertoire group had lower Gestational Age, lower Birth Weight, lower Apgar scores at birth and lower Developmental Quotient at 2 years. Eye and Hand Coordination (subscale D) was the domain mostly responsible for such a difference. Quality of fidgety movements (normal or abnormal fidgety) at 3 months did not show any correlation with outcome measures at 2 years.

Conclusion

The presence of a PR pattern at 1 month post-term seems to predict lower neurodevelopmental scores at 2 years especially in the domain of eye and hand coordination. Longer follow-up is necessary in order to ascertain if such difference will continue to persist at older ages.