Levetiracetam-associated loss of libido and anhedonia

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• 作者：Rocco S. Calabrò ; ; ^{salbro77@tiscali.it} ; Domenico Italiano ; David Militi ; Placido Bramanti
• 关键词：Loss of libido ; Anhedonia ; Levetiracetam ; Sexual dysfunction
• 刊名：Epilepsy & Behavior
• 出版年：2012
• 期刊代码：76_15255050
• 类别：neu
• 出版时间：June, 2012
• 卷：24
• 期：2
• 页码：283-284
• 文件大小：121 K

摘要

The relationship between the older antiepileptic drugs (AEDs) and sexual dysfunction has long been known and it is likely to be related to sexual hormonal changes. Instead, rare reports on sexual disorders related to new AEDs suggest the possibility of complex and poorly understood mechanisms, mainly involving central nervous system neurotransmitters such as glutamate, serotonin, and dopamine. Herein, we describe two young men with epilepsy who experienced severe loss of libido and anhedonia after levetiracetam intake.