• 作者：R. Morillo Verdugo^a ; ^{ralejandro.morillo.sspa@juntadeandalucia.es} ; L.C. Ferná ; ndez Lisó ; n^b ; M.J. Huertas Ferná ; ndez^c ; M.T. Martí ; n Conde^d ; J.C. Roldan Morales^e ; R. Ruano Camps^f ; J.I. Serrano Ló ; pez De Las Hazas^g ; O. Ibarra Barrueta^h ; A. Illaro Urangaⁱ
• 关键词：Efectos adversos ; Antirretrovirales ; Farmacé ; utico de hospital
• 刊名：Farmacia Hospitalaria
• 出版年：2010
• 期刊代码：pca388_11306343
• 类别：pha
• 出版时间：September-October 2010
• 卷：34
• 期：5
• 页码：237-250
• 文件大小：259 K

At present, the side effects associated with antiretroviral treatment are the main reasons for discontinuation of this kind of therapy, both in clinical trials and in regular clinical practise.

On the other hand, due to the change of direction that our profession has suffered in recent years, we face the need to establish a different relationship with the patient, achieving direct and effective Pharmaceutical Care within a framework of shared responsibility for therapeutic results.

Pharmacist interventions should be aimed at improving the quality of life of patients, which can only be achieved with a multidisciplinary approach and individualised and adjusted to new patterns of toxicity of the drugs currently used.

The pharmacist who does this work must know how to interpret these side effects, giving accurate information to the patient about both pharmacological and non-pharmacological treatment and correct pharmaceutical follow-up which clearly sets forth the criteria for referral to medical appointments.

The aim of this paper is to establish baselines so that the hospital pharmacist can perform clearly and uniformly in the prevention, identification and management of major side effects: gastrointestinal, cardiovascular, dermatological, at the central nervous system and kidney level, associated with antiretroviral therapy.