L24 Co-crystals: An emerging approach to improving properties of pharmaceutical solids

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• 作者：Sabiruddin Mirza ; Jyrki Heinä ; mä ; ki ; Inna Miroshnyk ; Jouko Yliruusi
• 关键词：Intra-arterial infusion chemotherapy ; Squamous cell carcinoma ; Oral cavity ; Midterm survival
• 刊名：European Journal of Pharmaceutical Sciences
• 出版年：2008
• 期刊代码：15_09280987
• 类别：pha
• 出版时间：9 June 2008
• 卷：34
• 期：1, Supplement 1
• 页码：S16-S17
• 文件大小：194 K

摘要

We performed superselective intra-arterial infusion chemotherapy (SIC) according to a protocol in which drug distribution is evaluated by the use of interventional radiology (IVR)-computed tomography (CT) system, and the chemotherapy is combined with medium-dose conformal radiation therapy (CRT). We analyzed retrospectively the factors that affect the midterm survival ratio, including local response, for stage III and IV squamous cell carcinomas of the oral cavity.