Unusual D:B-friedobaccharane and oxygenated friedelane-type triterpenoids from Salvadorean Celastraceae species

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• 作者：Marvin J. Nú ; ñ ; ez^a ; ^b ; Alejandro E. Ardiles^a ; Morena L. Martí ; nez^b ; David Torres-Romero^c ; Ignacio A. Jimé ; nez^a ; Isabel L. Bazzocchi^a ; ^{ilopez@ull.es}
• 关键词：Cassine xylocarpa ; Celastrus vulcanicola ; Celastraceae ; D ; B-friedobaccharane ; D ; A-friedooleanane
• 刊名：Phytochemistry Letters
• 出版年：2012
• 期刊代码：P8_18743900
• 类别：abs
• 出版时间：June, 2012
• 卷：5
• 期：2
• 页码：244-248
• 文件大小：262 K

摘要

Three new triterpenoids, including two rare D:B-friedobaccharanes (leonatriol, boldFont">1 and leonatriolone, boldFont">2) and a 2,3-seco-2,24-epoxy-3,24-olide-D:A-friedooleanane (cassinolide, boldFont">3) were isolated from the root bark of Cassine xylocarpa and Celastrus vulcanicola, collected in El Salvador. Their stereostructures were elucidated on the basis of spectroscopic analyses, mainly ¹D and ²D NMR techniques, spectrometric analyses, and comparison with data reported in the literature. The absolute configuration of boldFont">1 and boldFont">2 were determined by the application of the Riguera ester procedure and biogenetic considerations. The possible biogenetic pathway for cassinolide (boldFont">3) is also discussed.