Analysis of laboratory sample rejections in the pre-analytical stage at an oncology center

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• 作者：Vivek Bhat^a ; ^{vivekbhat2005@yahoo.com} ; Manikchandra Tiwari^b ; Preeti Chavan^a ; Rohini Kelkar^b
• 关键词：Sample rejection ; Pre-analytical ; Hematology ; Biochemistry ; Microbiology
• 刊名：Clinica Chimica Acta
• 出版年：2012
• 期刊代码：54_00098981
• 类别：med
• 出版时间：16 August, 2012
• 卷：413
• 期：15-16
• 页码：1203-1206
• 文件大小：135 K

摘要

<h4 class="h4">Backgroundh4>Effective patient management depends on the accuracy of laboratory results. Sample collection errors constitute an important reason for repeat collections. This study was conducted at the laboratory diagnostic services of a tertiary care oncology center with a hematopoietic stem cell transplant unit to determine the common causes of sample rejections and see the effects of corrective action.<h4 class="h4">Methodsh4>

A retrospective, intervention and prospective analysis of the samples rejected from the total samples received in our laboratories, during a nine month period from January to September 2011 was undertaken. Causes of sample rejections were determined and intervention in the form of training relevant staff was instituted.<h4 class="h4">Resultsh4>

Out of 32,548 samples received during Jan-Sep 2011, 177 samples (0.54%) were rejected. The most common reasons for rejection in hematology and biochemistry areas were clotted blood specimen (51.2%), improperly labeled specimen containers (14.46%) and hemolyzed blood samples (11.45%). For microbiology these included labeling errors, collection of specimen in wrong containers and specimen collection date and time not being entered, unacceptable specimen source and delayed transit time (18.2%each).<h4 class="h4">Conclusionsh4>

Directed interventions may help reduce the incidence of sample rejections.