• 作者：Julio Nú ; ñ ; ez ; ^{yulnunez@gmail.com} ; Juan Sanchis ; Vicent Bodí
• 关键词：Sí ; ndrome coronario sin elevació ; n del segmento ST ; Estrategia invasive ; Pronó ; stico
• 刊名：Medicina Cl铆nica
• 出版年：2009
• 期刊代码：pca254_00257753
• 类别：med
• 出版时间：14 November 2009
• 卷：133
• 期：18
• 页码：717-723
• 文件大小：156 K

Revascularization strategy in the setting of non-ST-segment acute coronary syndromes remains a controversy. Evidence obtained from clinical trials, generally performed in selected patients, reveals heterogeneous and insufficient results when a routine invasive revascularization strategy and a conservative one are compared. The conflicting results among trials are due to differences in: a) baseline characteristics; b) methodology and protocols applied and; c) objectives and outcomes definitions. Although present guidelines recommend that a routine invasive strategy should be used in high risk non-ST-segment elevation acute coronary syndromes, there is no consistent evidence that supports this approach. In order to reach definitive conclusions, further randomized studies should: a) expand inclusion criteria to highest risk populations and; b) standardize the methodology, objectives and outcome definitions.