Semisynthesis of labdane diterpene metabolites from the nudibranch Pleurobranchaea meckelii

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• 作者：Albert W.W. van Wyk ; Michael T. Davies-Coleman
• 关键词：Manool ; Labdane diterpene ; Marine ; Nudibranch ; Pleurobranchaea meckelii
• 刊名：Tetrahedron
• 出版年：2007
• 期刊代码：107_00404020
• 类别：ch
• 出版时间：3 December 2007
• 卷：63
• 期：49
• 页码：12179-12184
• 文件大小：203 K

摘要

Two isomeric labdane aldehyde metabolites (1 and 2), first isolated from the skin of the Notaspidean nudibranch Pleurobranchaea meckelii, were synthesized in six steps from manool in 19 and 6%overall isolated yields, respectively.