Valoraci贸n anatomopatol贸gica e inmunohistoqu铆mica frente a Treponema pallidum en 42 biopsias con sospecha clinicopatol贸gica de s铆filis
- 作者：Cristian Pernaa ; cristianperna@yahoo.es ; Jesú ; s Cuevasa ; David Hardissonb ; Eugenia Garcí ; a Ferná ; ndeza ; Maria José ; Beatob ; Fé ; lix Contrerasb
- 关键词：Sí ; filis ; Inmunohistoquí ; mica ; Treponema pallidum
- 刊名：Revista Espa帽ola de Patolog铆a
- 出版年：2011
- 期刊代码：pca318_16998855
- 类别：med
- 出版时间：July-September 2011
- 卷：44
- 期：3
- 页码：145-150
- 文件大小：792 K
摘要
Syphilis is a sexually transmitted disease which is still common. Traditionally, serology has been the diagnostic gold standard. The pathology of the lesions, especially those of secondary syphilis, can vary. Spirochetes (Treponema pallidum) can be detected with silver staining, but with only low sensitivity. Since the 1990s, immunohistochemistry against Treponema has been available. The pathology and immunohistochemistry of 42 biopsies from patients with a possible clinical diagnosis of syphilis were examined. In secondary syphilis, treponemas were detected in 83.3%of the cases using immunohistochemistry.