• 作者：P. Almagro^a ; ^{palmagro@mutuaterrassa.es} ; ^{19908pam@comb.cat} ; F. Ló ; pez^b ; F.J. Cabrera^c ; J. Portillo^d ; M. Fern&#225 ; ndez-Ruiz^e ; E. Zubillaga^f ; J. Dí ; ez^g ; P. Rom&#225 ; n^h ; J. Murcia-Zaragoza^b ; R. Boixedaⁱ ; C. Murio^j ; J.B. Soriano^k ; Grupos de trabajo de EPOC y Paciente Pluripatoló ; gico y Edad Avanzada de la Sociedad Espa&ntilde ; ola de Medicina Interna^&loz ;
• 关键词：Enfermedad pulmonar obstructiva cró ; nica ; Comorbilidad ; Hospitalizació ; n
• 刊名：Revista Cl铆nica Espa帽ola
• 出版年：2012
• 期刊代码：pca307_00142565
• 类别：med
• 出版时间：June, 2012
• 卷：212
• 期：6
• 页码：281-286
• 文件大小：237 K

lass="h4">Backgrounds and objectives

The presence of associated diseases is very frequent in patients hospitalized due to exacerbation of COPD. We have studied the comorbidities of patients admitted due to the disease in the Spanish Internal Medicine Services and we have evaluated the variations in regards to a previous study (ECCO study) performed two years earlier.

lass="h4">Patients and methods

A cross-sectional, multicenter and cohort study was performed. Patients hospitalized due to exacerbation of COPD in Spanish Internal Medicine Services were enrolled. All the patients were studied for the presence of comorbidity using the Charlson index and a questionnaire with relevant conditions not included in this index. Furthermore, spirometric data were collected on the duration of the disease or home treatment, among other variables.

lass="h4">Results

A total of 1004 patients (398 in the ECCO study and 606 in the ESMI study) were studied. Of these, 89.4%were males, with mean age of 73 years (SD: 9.5 years). The patients of the ESMI study obtain higher scores on the Charlson index (3.04 vs. 2.71; P<0.01), and had a greater prevalence of ischemic heart disease (17 vs. 22.0%; P<0.05), heart failure (26.9 vs. 35.5%; P<.002), peripheral vascular disease (12.6 vs. 17.4%; P<.02), arterial hypertension (54.8 vs. 65.6%; P<.001), diabetes mellitus (29.4 vs. 37%; P<.02) and renal failure (6.5 vs. 16.8%; P<.0001).

lass="h4">Conclusions

This study confirms the elevated prevalence of associated diseases in patients with COPD who are admitted to the Spanish Internal Medicine Services and the increase of comorbidities.