The Stockholm Neonatal Family-Centered Care Study: Effects on salivary cortisol in infants and their mothers

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• 作者：Evalotte Mö ; relius^a ; ^{evalotte.morelius@liu.se} ; Eva Berggren Broströ ; m^b ; Bjö ; rn Westrup^b ; Ihsan Sarman^c ; Annica Ö ; rtenstrand^c
• 关键词：Clinical Risk Index for Babies ; CRIB ; Family Care ; FC ; Gestational Age ; GA ; General Linear Model ; GLM ; Hypothalamus Pituitary Adrenal ; HPA ; Neonatal Intensive Care Unit ; NICU ; Standard Care ; SC
• 刊名：Early Human Development
• 出版年：2012
• 期刊代码：82_03783782
• 类别：med
• 出版时间：July, 2012
• 卷：88
• 期：7
• 页码：575-581
• 文件大小：587 K

摘要

Background

Parental involvement in the care of preterm infants in neonatal intensive care units (NICUs) is common, but little is known about the effect on stress responses in mothers and infants.

Aims

The aim of this study is to evaluate the effect of family-centered care on salivary cortisol reactivity in mothers and preterm infants and the correlation between the mothers' and the preterm infants' salivary cortisol levels.

Methods

This study is part of a randomized controlled trial conducted at two level-II NICUs, including Family Care (FC), where parents were able to stay 24 h/day from admission to discharge, and Standard Care (SC). To investigate the cortisol response, saliva was collected from 289 preterm infants and their mothers before and after a diaper change at the time of discharge.

Results

No significant differences were found between the two groups in salivary cortisol reactivity, either in mothers or in infants. The results revealed a correlation between preterm infants' and their mothers' baseline and response cortisol in the FC group: r = 0.31 (p = 0.001) and r = 0.24 (p = 0.01), respectively. Such correlation was not observed in the SC group: r = 0.14 (p = 0.14) and r = 0.18 (p = 0.07), respectively.

Conclusions

Family-centered care had no effect on salivary cortisol reactivity during diaper change. However, sharing the same environment may increase the concordance between preterm infants' and their mothers' salivary cortisol levels.