Levels and profiles of PCDD/Fs, PCBs in mothers' milk in Shenzhen of China: Estimation of breast-fed infants鈥?intakes

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• 作者：Bo Deng^a ; ^b ; JianQing Zhang^a ; ^{zhjianqing95@gmail.com} ; Lishi Zhang^c ; YouSheng Jiang^a ; Jian Zhou^a ; Daokui Fang^a ; Huiming Zhang^a ; HaiYan Huang^a
• 关键词：Body burden ; Polychlorinated dibenzo-p-dioxins ; Polychlorinated dibenzofurans ; Polychlorinated biphenyls ; Estimated daily intakes (EDI) ; Human breast milk
• 刊名：Environment International
• 出版年：2012
• 期刊代码：25_01604120
• 类别：env
• 出版时间：July, 2012
• 卷：42
• 期：Complete
• 页码：47-52
• 文件大小：199 K

摘要

Sixty breast milk samples were collected in Shenzhen, China from July to November in 2007. The samples were analyzed of the concentrations of polychlorinated dibenzo-p-dioxins (PCDDs), polychlorinated dibenzofurans (PCDFs) and polychlorinated biphenyls (PCBs). The range of upper-bound for 鈭?#xA0;TEQ-(PCDD/Fs + PCBs) in the samples was 4.10-35.3 pg TEQ g^鈭?#xA0;1 lipid (median: 10.6 pg TEQ g^鈭?#xA0;1 lipid; mean: 11.9 pg TEQ g^鈭?#xA0;1 lipid). The levels of the measured contaminants in the breast milk had significant correlations with the length of inhabitation period in Shenzhen (r = 0.487, p < 0.05 for PCDD/Fs, r = 0.431, p < 0.05 for PCBs and r = 0.478, p < 0.05 for 鈭?#xA0;TEQ-(PCDD/Fs + PCBs)), and the consumption rate of fish (r = 0.366, p < 0.05 for PCDD/Fs, r = 0.486, p < 0.05 for PCBs and r = 0.416, p < 0.05 for 鈭?#xA0;TEQ-(PCDD/Fs + PCBs)), respectively. Moreover, significant positive correlations were also detected between the participant's age (r = 0.305, p < 0.05 for 鈭?#xA0;TEQ-PCBs and r = 0.275, p < 0.05 for 鈭?#xA0;TEQ-(PCDD/Fs + PCBs)) and the body burdens of these contaminants respectively. It is estimated that the daily intake (EDI) of the sum of PCDD/Fs and DL-PCBs by the breast-fed infants was 5.60-161 pg TEQ kg^鈭?#xA0;1 bw per day (mean: 48.2 pg TEQ kg^鈭?#xA0;1 bw per day; median: 42.2 pg TEQ kg^鈭?#xA0;1 bw per day). The result showed that both the body burdens of PCDD/Fs and PCBs of the recruit population and the calculated EDI of the breast-fed infants were higher than those in the non-exposed areas in mainland China. This suggests that continuous surveillance on PCDD/Fs and PCBs levels in human milk is critical to more precisely evaluate the human health risk posed by the negative environmental impact in Shenzhen in the future.