• 作者：Laura Pé ; rez Delgado^a ; ^{layipez@hotmail.com} ; Mahfoud El Uali Abeida^a ; Fé ; lix de Miguel Garcí ; a^a ; Pilar Astier Peñ ; a^b ; Silvia Herrera Tolosana^a ; Maria Pilar Lisbona Alqué ; zar^a ; Gloria Tejero-Garcé ; s Galve^a ; Jorge Sevil Navarro^a ; Ramó ; n Martinez-Berganza^a ; Alberto Ortiz Garcí ; a^a
• 关键词：Carcinoma supragló ; tico ; Laringectom&iacute ; a supragló ; tica lá ; ser ; Cá ; ncer de laringe
• 刊名：Acta Otorrinolaringol贸gica Espa帽ola
• 出版年：2010
• 期刊代码：pca34_00016519
• 类别：med
• 出版时间：January-February 2010
• 卷：61
• 期：1
• 页码：12-18
• 文件大小：202 K

Introduction and objetives

The study goal was to analyze the oncologic and functional outcomes of transoral laser microsurgery in the treatment of carcinoma of the supraglottic larynx.

Material and methods

A total of 53 patients were included in this retrospective review between 2000 and 2006. The follow-up period was more than 2 years and the mean follow-up for all patients was 49 months.

Results

Tumour extension was as follows: T1 in 12 (22.6%), T2 in 37 (69.8%) and T3 in 4 (7.5%). Forty-seven patients (88.7%) had neck dissections. Nineteen patients (35.8%) received adjuvant radiotherapy. Kaplan-Meier estimates for disease-specific survival were 80%, 74.11%and 65%, at 2, 3 and 5 years, respectively. The overall functional laryngeal preservation rate was 90.56%. (48 of 53), and local control 81.13%. During follow up, 13.2%of patients developed local recurrence, 11.3%regional recurrence and 5.7%loco-regional recurrence. Patients started swallowing early after surgery, with a mean time of 5.83 days, and the mean hospital stay was 14.69 days. Complications included 20.75%who suffered pneumonia and 11.32%with bleeding. Only one patient (1.88%) received total laryngectomy due to the impossibility of swallowing.

Conclusions

With careful selection of patients, laser supraglottic laryngectomy is a safe and effective treatment for cancer of the supraglottic larynx.