High impact of depression in heart failure: Early diagnosis and treatment options
- 作者：Christine Norra ; Eric C. Skobel ; Marlies Arndt ; Patrick Schauerte
- 关键词：Depression ; Chronic heart failure ; Risk factors ; Pathogenesis ; Diagnosis ; Antidepressant treatment
- 刊名：International Journal of Cardiology
- 出版年：2008
- 期刊代码：128_01675273
- 类别：med
- 出版时间：10 April 2008
- 卷：125
- 期：2
- 页码：220-231
- 文件大小：259 K
摘要
Depressive syndromes in chronic heart failure (CHF) are common and are associated with a poorer prognosis, particularly with increased morbidity and mortality. CHF as a severe physical disorder may increase the risk of developing depressive syndromes or vice-versa as an interaction of possible common psycho-organic etiological aspects. Depression in CHF is associated with impaired NYHA status and daily activities, resulting in enhanced hospitalisation rates and medical costs with a great impact on long-term health. Only a fraction of comorbid patients receives antidepressants. Therefore, identification of risk factors and prevention by optimizing cardiological and psychiatric therapeutic strategies appear essential for these patients. Early diagnosis and treatment of both CHF and depression may prevent further pathophysiological effects on the heart and brain.