Ambient temperature-dependent thermoregulatory role of REM sleep

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• 作者：Deependra Kumar¹ ; ^{kdeepen@gmail.com} ; Velayudhan Mohan Kumar² ; ^{wfsrs2005@rediffmail.com} ; Hruda Nanda Mallick ; ¹ ; ^{drhmallick@yahoo.com}
• 关键词：Ambient temperature ; Tamb ; Body temperature ; Tb ; Sleep&ndash ; wakefulness ; S&ndash ; W ; Total sleep time ; TST ; Slow wave sleep ; SWS
• 刊名：Journal of Thermal Biology
• 出版年：2012
• 期刊代码：100_03064565
• 类别：bio
• 出版时间：August, 2012
• 卷：37
• 期：5
• 页码：392-396
• 文件大小：758 K

摘要

Changes in ambient temperature produce complex effects on sleep-wakefulness. In order to find out the mechanisms involved in temperature-sensitive changes in sleep in rats, their thermal preference, body temperature and sleep were studied before and after the destruction of both peripheral and central warm receptors, by systemic administration of 375 mg/kg capsaicin. Though the pre-treated rats preferred to stay mostly at the ambient temperature of 27 掳C, post-treated rats strayed freely into chambers having ambient temperature of 30 掳C and 33 掳C. Sleep and body temperature of these rats were studied for six hours each, when they were kept at an ambient temperature of 18-36 掳C. Total sleep time, especially REM sleep, was maximum at 30 掳C in pre-treated rats, but this REM sleep peak at 30 掳C disappeared after capsaicin administration. Body temperature increased sharply in post-treated rats, at ambient temperatures above 30 掳C. Apart from the ability to defend body temperature at high ambient temperature, avoidance of warm ambient temperature and increase in REM sleep are the behavioral measures which are lost in post-treated rats. Results of this study suggest that the ambient temperature-related increase in REM sleep at 30 掳C could be part of the thermoregulatory measures.