A novel approach for the synthesis of alkyl and aryl sulfonamides

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• 作者：Ahmad Shaabani ; Ebrahim Soleimani ; Ali Hossein Rezayan
• 关键词：Isocyanide ; Sulfonamides ; Sulfonic acid
• 刊名：Tetrahedron Letters
• 出版年：2007
• 期刊代码：109_00404039
• 类别：ch
• 出版时间：19 March 2007
• 卷：48
• 期：12
• 页码：2185-2188
• 文件大小：131 K

摘要

A novel approach for the synthesis of alkyl and aryl sulfonamides by the reaction of sulfonic acids, isocyanides and water in dichloromethane is reported at ambient temperature in excellent yields within 20 min. To the best of our knowledge this is the first report on the synthesis of this biologically important family using easily available sulfonic acids and isocyanides.