• 作者：Leandro Alberto de Sousa ; PT ; DO ^{leandroalbertodesousa@hotmail.com}
• 关键词：Hiperamonemia ; Amonio sé ; rico ; Insuficiencia hepá ; tica aguda ; Alteraciones gené ; ticas del metabolism
• 刊名：Osteopat铆a Cient铆fica
• 出版年：2011
• 期刊代码：pca274_18869297
• 类别：med
• 出版时间：January-April 2011
• 卷：6
• 期：1
• 页码：19-29
• 文件大小：302 K

Objective

To demonstrate that Ralph Faylor's liver pumping technique does not reduce plasma ammonia levels in individuals with levels above 45 渭Mol/L to levels considered normal.

Patients, materials and methods

We performed a single-blind randomized clinical trial in 31 patients with ammonia levels above 45 渭Mol/L, divided in two groups. There were 16 patients in the treatment group and 15 in the control group. In both groups, ammonia levels were measured at five distinct time points: test 1, before the first intervention; test 2, within 7 to 10 min after the first intervention; test 3, 24 h after the first intervention; test 4, 7 days after the first intervention; and test 5, within 7 to 10 min after the fourth intervention (one intervention per week) following the pre-established protocol.

Results

Statistical analysis revealed that the technique and/or its simulation produced no change in serum ammonia levels (P > .05).

Conclusion

In patients with plasma ammonia levels above 45 渭Mol/L, Ralph Failor's liver pumping technique cannot reduce blood concentrations of this metabolite.