Life events and social rhythms in bipolar spectrum disorders: An examination of social rhythm sensitivity

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• 作者：Elaine M. Boland^a ; ; Rachel E. Bender^a ; Lauren B. Alloy^a ; Bradley T. Conner^a ; Denise R. LaBelle^a ; Lyn Y. Abramson^b
• 关键词：Bipolar disorder ; Social rhythms ; Circadian rhythms ; Life events
• 刊名：Journal of Affective Disorders
• 出版年：2012
• 期刊代码：141_01650327
• 类别：med
• 出版时间：August, 2012
• 卷：139
• 期：3
• 页码：264-272
• 文件大小：200 K

摘要

Objectives

To examine the presence of an underlying social rhythm sensitivity in individuals with bipolar spectrum disorders.

Methods

The present study examined the impact of life events on sleep loss and social rhythm disruption in 184 individuals with bipolar spectrum disorders (BSD) compared to 197 demographically similar normal controls (NC) drawn from the Longitudinal Investigation of Bipolar Spectrum Disorders (LIBS) project. Life events data were obtained at three time points, each spaced four months apart, and included information on the intensity of the event (high or low), valence (negative or positive), and levels of sleep loss and social rhythm disruption brought about the event. We hypothesized that BSD participants would exhibit higher levels of social rhythm disruption and sleep loss than normal controls as a consequence of the same life events.

Results

BSD participants experienced significantly more social rhythm disruption and sleep loss following all classes of life events.

Limitations

The cross-sectional design of this study limits the strength of the conclusions that can be drawn, primarily cause and effect relationships between social rhythms and symptoms.

Conclusions

Findings support the presence of an underlying social rhythm sensitivity in individuals with bipolar spectrum disorders. An additive effect of sleep loss and social rhythm disruption may contribute to subsequent mood symptomatology. Results from this study may inform early psychosocial interventions for at-risk individuals.