An efficient, eco-friendly process for aldol and Michael reactions of trimethylsilyl enolate over organic base-functionalized SBA-15 catalysts
- 作者：Rajendra Srivastava
- 关键词：Aldol reaction ; Michael reaction ; Organic bases ; Lewis bases ; Heterogeneous catalyst ; SBA-15
- 刊名：Journal of Molecular Catalysis A ; Chemical
- 出版年：2007
- 期刊代码：57_13811169
- 类别：ch
- 出版时间：1 March 2007
- 卷：264
- 期：1-2
- 页码：146-152
- 文件大小：401 K
摘要
1,5,7-Triazabicyclo[4.4.0]dec-5-ene (TBD, a bicyclic guanidine base) functionalized SBA-15 was found to be an efficient catalyst for aldol reaction of trimethylsilyl enolate with aldehydes. Both aryl aldehydes and alkyl aldehydes provided aldol products in good yields. The applicability of this catalyst was extended to Michael reaction and in the synthesis of quaternary carbon. This novel heterogeneous catalyst offers several attractive advantages over soluble base catalysts such as high catalyst activity under mild reaction condition, easy recovery and reusability of the catalyst.