Marrow-derived cells populate scaffolds composed of xenogeneic extracellular matrix

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• 作者：Badylak ; Stephen F. ; Park ; Kinam ; Peppas ; Nicholas ; McCabe ; George ; Yoder ; Mervin
• 刊名：Experimental Hematology
• 出版年：2001
• 期刊代码：100_0301472x
• 类别：med
• 出版时间：November, 2001
• 卷：29
• 期：11
• 页码：1310-1318
• 文件大小：565 K

摘要

The source of cells that participate in wound repair directly affects outcome. The extracellular matrix (ECM) and other acellular biomaterials have been used as therapeutic scaffolds for cell attachment and proliferation and as templates for tissue repair. The ECM consists of structural and functional proteins that influence cell attachment, gene expression patterns, and the differentiation of cells.