Relapse of ocular symptoms after remission of myasthenia gravis—a comparison of relapsed and complete remission cases

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• 作者：Wakata ; Nobuo ; Iguchi ; Hiroaki ; Sugimoto ; Hideki ; Nomoto ; Nobuatu ; Kurihara ; Teruyuki
• 关键词：Myasthenia gravis ; Relapsing myasthenia gravis ; Complete remission myasthenia gravis ; EOM fiber
• 刊名：Clinical Neurology and Neurosurgery
• 出版年：2003
• 期刊代码：60_03038467
• 类别：med
• 出版时间：April, 2003
• 卷：105
• 期：2
• 页码：75-77
• 文件大小：141 K

摘要

Extended thymectomy and high-dose alternate-day prednisolone administration may increase the chance of remission in myasthenia gravis (MG) patients. In cases of remission, ocular symptoms sometimes reappear after a gradual decrease or discontinuation of prednisolone administration. We compared relapsed patients with those who experienced complete remission. We found that the period from onset of MG to thymectomy and initiation of prednisolone administration was longer in the relapsed cases, which suggests that early thymectomy and administration of prednisolone can lead to a superior outcome in MG patients.