We present the results of measurement of grains vibrations under external action in gas and liquid with a laser heterodyne receiver of scattered radiation. For investigation of dynamic characteristics of particles we made the laser heterodyne receiver with sensitivity about 2×10−17 W/Hz and source of probing with radiation power 1 mW. In our pilot experiments, measurement of vibration amplitude of nanoparticles in gas (cigarette smoke) and microparticles in fluid (toothpaste in water) was made. We measured values of vibration amplitudes about 20–30 nm.