Three-dimensional microtomographic imaging of human brain cortex
- 作者：Ryuta Mizutani ; Akihisa Takeuchi ; Kentaro Uesugi ; Masami Ohyama ; Susumu Takekoshi ; R. Yoshiyuki Osamura ; Yoshio Suzuki
- 关键词：Microtomography ; CT ; Pyramidal neuron ; Golgi impregnation ; Microcontrasting
- 刊名：Brain Research
- 出版年：2008
- 期刊代码：8_00068993
- 类别：neu
- 出版时间：14 March 2008
- 卷：1199
- 期：Complete
- 页码：53-61
- 文件大小：4774 K
摘要
This paper describes an X-ray microtomographic technique for imaging the three-dimensional structure of the human cerebral cortex. Neurons in the brain constitute a neural circuit as a three-dimensional network. The brain tissue is composed of light elements that give little contrast in a hard X-ray transmission image. The contrast was enhanced by staining neural cells with metal compounds. The obtained structure revealed the microarchitecture of the gray and white matter regions of the frontal cortex, which is responsible for the higher brain functions.