Stereoselective synthesis of 3,4-disubstituted tetrahydrofurans and 2,3,4-trisubstituted tetrahydrofurans using an intramolecular allylation strategy employing allylsilanes
- 作者：Peter J. Jervis ; Benson M. Kariuki ; Liam R. Cox
- 关键词：Allylsilanes ; Tetrahydrofurans ; Cyclisation ; Intramolecular allylation ; Brø ; nsted acids
- 刊名：Tetrahedron Letters
- 出版年：2008
- 期刊代码：109_00404039
- 类别：ch
- 出版时间：14 April 2008
- 卷：49
- 期：16
- 页码：2514-2518
- 文件大小：236 K
摘要
A Brønsted acid-mediated intramolecular allylation involving an allylsilane and an aldehyde has been used as the key step in a stereoselective synthesis of 3,4-disubstituted tetrahydrofurans and 2,3,4-trisubstituted tetrahydrofurans.