Facile synthesis of 9-(arenethenyl)purines via Heck reaction of 9-vinylpurines and aryl halides

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• 作者：Wei-Sheng Huang ; Yihan Wang ; Raji Sundaramoorthi ; R. Mathew Thomas ; David Wen ; Shuangying Liu ; Scott P. Lentini ; Sasmita Das ; Geetha B ; a ; Tomi K. Sawyer ; William C. Shakespeare
• 关键词：9-Vinylpurine ; Heck reaction ; 9-(Arenethenyl)purine ; 9-(Arenethyl)purine
• 刊名：Tetrahedron Letters
• 出版年：2007
• 期刊代码：109_00404039
• 类别：ch
• 出版时间：8 October 2007
• 卷：48
• 期：41
• 页码：7388-7391
• 文件大小：126 K

摘要

The first example of a Heck reaction with 9-vinylpurines and aryl halides is described. It gives exclusively E-9-(arenethenyl)purines in high yields. Subsequent hydrogenation furnishes 9-(arenethyl)purines quantitatively.