Unified Protocol for Transdiagnostic Treatment of Emotional Disorders: A Randomized Controlled Trial

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• 作者：Todd J. Farchione^a ; ^{tfarchio@bu.edu} ; Christopher P. Fairholme^a ; Kristen K. Ellard^a ; Christina L. Boisseau^b ; Johanna Thompson-Hollands^a ; Jenna R. Carl^a ; Matthew W. Gallagher^a ; David H. Barlow^a
• 关键词：anxiety disorders ; cognitive-behavioral treatment ; transdiagnostic ; unified protocol
• 刊名：Behavior Therapy
• 出版年：2012
• 期刊代码：2_00057894
• 类别：psy
• 出版时间：September, 2012
• 卷：43
• 期：3
• 页码：666-678
• 文件大小：300 K

摘要

This study further evaluates the efficacy of the Unified Protocol for Transdiagnostic Treatment of Emotional Disorders (UP). A diagnostically heterogeneous clinical sample of 37 patients with a principal anxiety disorder diagnosis was enrolled in a randomized controlled trial (RCT) involving up to 18 sessions of treatment and a 6-month follow-up period. Patients were randomly assigned to receive either immediate treatment with the UP (n = 26) or delayed treatment, following a 16-week wait-list control period (WLC; n = 11). The UP resulted in significant improvement on measures of clinical severity, general symptoms of depression and anxiety, levels of negative and positive affect, and a measure of symptom interference in daily functioning across diagnoses. In comparison, participants in the WLC condition exhibited little to no change following the 16-week wait-list period. The effects of UP treatment were maintained over the 6-month follow-up period. Results from this RCT provide additional evidence for the efficacy of the UP in the treatment of anxiety and comorbid depressive disorders, and provide additional support for a transdiagnostic approach to the treatment of emotional disorders.